› 2bvu

X-ray diffraction
2.5Å resolution

D83R mutant of Asaris suum major sperm protein (MSP)

Released:
DOI: 10.2210/pdb2bvu/pdb
PDB entry 2bvu coloured by chain, front view.
PDB entry 2bvu coloured by chain, side view.
PDB entry 2bvu coloured by chain, top view.
Source organism: Ascaris suum
Primary publication:
The role of filament-packing dynamics in powering amoeboid cell motility.
Miao L, Vanderlinde O, Liu J, Grant RP, Wouterse A, Shimabukuro K, Philipse A, Stewart M, Roberts TM
Proc Natl Acad Sci U S A 105 5390-5 (2008)
PMID: 18385381

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151002 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Major sperm protein isoform alpha Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 126 amino acids
Theoretical weight: 14.32 KDa
Source organism: Ascaris suum
Expression system: Escherichia coli
UniProt:
  • Canonical: P27439 (Residues: 2-127; Coverage: 99%)
Sequence domains: MSP (Major sperm protein) domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX14.1
Spacegroup: P41212
Unit cell:
a: 54.805Å b: 54.805Å c: 453.14Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.23 0.226 0.291
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Mechanical modes of 'amoeboid' cell migration.
Lämmermann et al. (2009)
2 more

1 mention without citation

The role of filament-packing dynamics in powering amoeboid cell motility.
Miao et al. (2008)