› 2dk3

Solution NMR

Solution structure of Mib-herc2 domain in HECT domain containing protein 1

Released:
DOI: 10.2210/pdb2dk3/pdb
PDB entry 2dk3 coloured by chain, ensemble of 20 models, front view.
PDB entry 2dk3 coloured by chain, ensemble of 20 models, side view.
PDB entry 2dk3 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: He F, Muto Y, Inoue M, Kigawa T, Shirouzu M, Terada T, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
(1a) S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [HECT-type E3 ubiquitin transferase]-L-cysteine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + S-ubiquitinyl-[HECT-type E3 ubiquitin transferase]-L-cysteine
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193929 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
E3 ubiquitin-protein ligase HECTD1 Chain: A
Molecule details ›
Chain: A
Length: 86 amino acids
Theoretical weight: 9.08 KDa
Source organism: Homo sapiens
Expression system: Cell free synthesis
UniProt:
  • Canonical: Q9ULT8 (Residues: 1266-1338; Coverage: 3%)
Gene names: HECTD1, KIAA1131
Sequence domains: Mib_herc2
Structure domains: SH3 Domains

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Cell free synthesis

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