› 2g0k

Solution NMR

Solution Structure of Neocarzinostatin Apo-Protein

Released:
DOI: 10.2210/pdb2g0k/pdb
PDB entry 2g0k coloured by chain, ensemble of 47 models, front view.
PDB entry 2g0k coloured by chain, ensemble of 47 models, side view.
PDB entry 2g0k coloured by chain, ensemble of 47 models, top view.
Source organism: Streptomyces carzinostaticus
Primary publication:
Synthetic ligands for apo-neocarzinostatin.
Caddick S, Muskett FW, Stoneman RG, Woolfson DN
J Am Chem Soc 128 4204-5 (2006)
PMID: 16568976

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-141217 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neocarzinostatin Chain: A
Molecule details ›
Chain: A
Length: 122 amino acids
Theoretical weight: 12.23 KDa
Source organism: Streptomyces carzinostaticus
Expression system: Escherichia coli
UniProt:
  • Canonical: P0A3R9 (Residues: 35-147; Coverage: 100%)
Gene name: ncsA
Sequence domains: Neocarzinostatin family
Structure domains: Neocarzinostatin-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Complexity and simplicity in the biosynthesis of enediyne natural products.
Liang ZX. (2010)
13 other articles

1 mention without citation

PDB2CD visualises dynamics within protein structures.
Janes RW. (2017)