› 2ins

X-ray diffraction
2.5Å resolution

THE STRUCTURE OF DES-PHE B1 BOVINE INSULIN

Released:
DOI: 10.2210/pdb2ins/pdb
PDB entry 2ins coloured by chain, front view.
PDB entry 2ins coloured by chain, side view.
PDB entry 2ins coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
The Structure of Des-Phe B1 Bovine Insulin
Smith GD, Duax WL, Dodson EJ, Dodson GG, Degraaf RAG, Reynolds CD
Acta Crystallogr., B 38 3028- (1982)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
hetero dodecamer
hetero hexamer
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134251 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Insulin A chain Chains: A, C
Molecule details ›
Chains: A, C
Length: 21 amino acids
Theoretical weight: 2.34 KDa
Source organism: Bos taurus
Expression system: Not provided
UniProt:
  • Canonical: P01317 (Residues: 85-105; Coverage: 26%)
Gene name: INS
Insulin B chain Chains: B, D
Molecule details ›
Chains: B, D
Length: 29 amino acids
Theoretical weight: 3.26 KDa
Source organism: Bos taurus
Expression system: Not provided
UniProt:
  • Canonical: P01317 (Residues: 26-54; Coverage: 36%)
Gene name: INS
Sequence domains: Insulin/IGF/Relaxin family

Ligands and Environments

1 bound ligand:
Ligand ZN 2 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: R3
Unit cell:
a: 81.6Å b: 81.6Å c: 34Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.18 0.18 not available
Expression system: Not provided

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Citations

15 mentions without citation

Structural diversity and biological significance of glycosphingolipids in pathogenic and opportunistic fungi.
Guimarães et al. (2014)
14 more