› 2j76

Solution NMR

Solution structure and RNA interactions of the RNA recognition motif from eukaryotic translation initiation factor 4B

Released:
DOI: 10.2210/pdb2j76/pdb
PDB entry 2j76 coloured by chain, front view.
PDB entry 2j76 coloured by chain, side view.
PDB entry 2j76 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure and RNA interactions of the RNA recognition motif from eukaryotic translation initiation factor 4B.
Fleming K, Ghuman J, Yuan X, Simpson P, Szendröi A, Matthews S, Curry S
Biochemistry 42 8966-75 (2003)
PMID: 12885229

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150020 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Eukaryotic translation initiation factor 4B Chain: E
Molecule details ›
Chain: E
Length: 100 amino acids
Theoretical weight: 11.46 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P23588 (Residues: 78-176; Coverage: 16%)
Gene name: EIF4B
Sequence domains: RNA recognition motif
Structure domains: Alpha-Beta Plaits

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this NMR entry.
Expression system: Not provided

Quick links

Citations

1 review citation

Translation initiation by cap-dependent ribosome recruitment: Recent insights and open questions.
Shirokikh et al. (2018)
12 other articles

4 mentions without citation

The DEAD-box helicase eIF4A: paradigm or the odd one out?
Andreou et al. (2013)
3 more