› 2j8b

X-ray diffraction
1.15Å resolution

High resolution structure of human CD59

Released:
DOI: 10.2210/pdb2j8b/pdb
PDB entry 2j8b coloured by chain, front view.
PDB entry 2j8b coloured by chain, side view.
PDB entry 2j8b coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
High-resolution structures of bacterially expressed soluble human CD59.
Leath KJ, Johnson S, Roversi P, Hughes TR, Smith RA, Mackenzie L, Morgan BP, Lea SM
Acta Crystallogr Sect F Struct Biol Cryst Commun 63 648-52 (2007)
PMID: 17671359

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146830 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
CD59 glycoprotein Chain: A
Molecule details ›
Chain: A
Length: 79 amino acids
Theoretical weight: 9.16 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P13987 (Residues: 26-103; Coverage: 76%)
Gene names: CD59, MIC11, MIN1, MIN2, MIN3, MSK21
Sequence domains: u-PAR/Ly-6 domain
Structure domains: CD59

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P212121
Unit cell:
a: 31.948Å b: 45.918Å c: 46.033Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.165 0.164 0.197
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Complement System Part I - Molecular Mechanisms of Activation and Regulation.
Merle et al. (2015)
1 more

14 mentions without citation

NMR structure and action on nicotinic acetylcholine receptors of water-soluble domain of human LYNX1.
Lyukmanova et al. (2011)
13 more