› 2jof

Solution NMR

The Trp-cage: Optimizing the Stability of a Globular Miniprotein

Released:
DOI: 10.2210/pdb2jof/pdb
PDB entry 2jof coloured by chain, ensemble of 28 models, front view.
PDB entry 2jof coloured by chain, ensemble of 28 models, side view.
PDB entry 2jof coloured by chain, ensemble of 28 models, top view.
Source organism: synthetic construct
Primary publication:
The Trp-cage: optimizing the stability of a globular miniprotein.
Barua B, Lin JC, Williams VD, Kummler P, Neidigh JW, Andersen NH
Protein Eng Des Sel 21 171-85 (2008)
PMID: 18203802

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-162786 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
TRP-CAGE Chain: A
Molecule details ›
Chain: A
Length: 20 amino acids
Theoretical weight: 2.09 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 46%
Refinement method: molecular dynamics, simulated annealing
Expression system: Not provided

Quick links

Citations

4 review citations

Assessing the accuracy of physical models used in protein-folding simulations: quantitative evidence from long molecular dynamics simulations.
Piana et al. (2014)
3 more

30 mentions without citation

The Uniqueness of Tryptophan in Biology: Properties, Metabolism, Interactions and Localization in Proteins.
Barik S. (2020)
29 more