› 2kgr

Solution NMR

Solution structure of protein ITSN1 from Homo sapiens. Northeast Structural Genomics Consortium target HR5524A

Released:
DOI: 10.2210/pdb2kgr/pdb
PDB entry 2kgr coloured by chain, ensemble of 20 models, front view.
PDB entry 2kgr coloured by chain, ensemble of 20 models, side view.
PDB entry 2kgr coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Wu Y, Ghosh A, Shastry R, Hua J, Ciccosanti C, Zhang Q, Jiang M, Swapna G, Acton T, Xiao R, Everett J, Montelione G, Szyperski T, Northeast Structural Genomics Consortium (NESG)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172413 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Intersectin-1 Chain: A
Molecule details ›
Chain: A
Length: 111 amino acids
Theoretical weight: 12.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q15811 (Residues: 210-312; Coverage: 6%)
Gene names: ITSN, ITSN1, SH3D1A
Sequence domains: Cytoskeletal-regulatory complex EF hand
Structure domains: EF-hand

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

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