› 2lbv

Solution NMR

Siderocalin Q83 reveals a dual ligand binding mode

Released:
DOI: 10.2210/pdb2lbv/pdb
PDB entry 2lbv coloured by chain, ensemble of 20 models, front view.
PDB entry 2lbv coloured by chain, ensemble of 20 models, side view.
PDB entry 2lbv coloured by chain, ensemble of 20 models, top view.
Source organism: Coturnix japonica
Primary publication:
Lipocalin Q83 reveals a dual ligand binding mode with potential implications for the functions of siderocalins.
Coudevylle N, Hoetzinger M, Geist L, Kontaxis G, Hartl M, Bister K, Konrat R
Biochemistry 50 9192-9 (2011)
PMID: 21951132

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-191517 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Extracellular fatty acid-binding protein Chain: A
Molecule details ›
Chain: A
Length: 157 amino acids
Theoretical weight: 18.1 KDa
Source organism: Coturnix japonica
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9I9P7 (Residues: 23-178; Coverage: 99%)
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

3 bound ligands:
Ligand EB4 1 x EB4
Ligand GA 1 x GA
Ligand ACD 1 x ACD
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 70%
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Cellular and mitochondrial iron homeostasis in vertebrates.
Chen et al. (2012)
1 more

1 mention without citation

Protein Structure Idealization: How accurately is it possible to model protein structures with dihedral angles?
Cui et al. (2013)