› 2lcz

Solution NMR

NMR Structure of the Complete Internal Fusion Loop from Ebolavirus GP2 at pH 7.0

Released:
DOI: 10.2210/pdb2lcz/pdb
PDB entry 2lcz coloured by chain, ensemble of 20 models, front view.
PDB entry 2lcz coloured by chain, ensemble of 20 models, side view.
PDB entry 2lcz coloured by chain, ensemble of 20 models, top view.
Source organism: Zaire ebolavirus
Primary publication:
Structure and function of the complete internal fusion loop from Ebolavirus glycoprotein 2.
Gregory SM, Harada E, Liang B, Delos SE, White JM, Tamm LK
Proc Natl Acad Sci U S A 108 11211-6 (2011)
PMID: 21690393

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-109034 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Envelope glycoprotein Chain: A
Molecule details ›
Chain: A
Length: 54 amino acids
Theoretical weight: 5.95 KDa
Source organism: Zaire ebolavirus
Expression system: Escherichia coli
UniProt:
  • Canonical: A9QPL9 (Residues: 507-560; Coverage: 8%)
Gene name: GP
Sequence domains: Envelope glycoprotein GP2-like, HR1-HR2

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 92%
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

19 review citations

Fusion of Enveloped Viruses in Endosomes.
White et al. (2016)
18 more

2 mentions without citation

Structure and function of the complete internal fusion loop from Ebolavirus glycoprotein 2.
Gregory et al. (2011)
1 more