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Solution NMR

NMR structure of Carcinoscorpius rotundicauda thioredoxin related protein 16 and its role in regulating transcription factor NF-kB activity

Released:
DOI: 10.2210/pdb2lus/pdb
PDB entry 2lus coloured by chain, ensemble of 20 models, front view.
PDB entry 2lus coloured by chain, ensemble of 20 models, side view.
PDB entry 2lus coloured by chain, ensemble of 20 models, top view.
Source organism: Carcinoscorpius rotundicauda
Primary publication:
NMR structure of Carcinoscorpius rotundicauda thioredoxin-related protein 16 and its role in regulating transcription factor NF-κB activity.
Giri PK, Jing-Song F, Shanmugam MK, Ding JL, Sethi G, Swaminathan K, Sivaraman J
J Biol Chem 287 29417-28 (2012)
PMID: 22763700

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-500083 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thioredoxin domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 143 amino acids
Theoretical weight: 16.06 KDa
Source organism: Carcinoscorpius rotundicauda
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: A3E0V9 (Residues: 1-143; Coverage: 100%)
Sequence domains: Thioredoxin-like
Structure domains: Glutaredoxin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 78%
Refinement method: torsion angle dynamics
Expression system: Escherichia coli BL21

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Citations

2 citation in other articles

Cooperatively transcriptional and epigenetic regulation of sonic hedgehog overexpression drives malignant potential of breast cancer.
Duan et al. (2015)
1 more

1 mention without citation

NMR structure of Carcinoscorpius rotundicauda thioredoxin-related protein 16 and its role in regulating transcription factor NF-κB activity.
Giri et al. (2012)