Function and Biology Details
Reactions catalysed:
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
Endonucleolytic cleavage to 5'-phosphomonoester.
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence domain:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Reverse transcriptase/ribonuclease H (preferred)
PDBe Complex ID:
PDB-CPX-136824 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Integrase
Molecule details ›
Chain: A
Length: 89 amino acids
Theoretical weight: 10.13 KDa
Source organism: Moloney murine leukemia virus isolate Shinnick
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Murine leukemia virus (MLV) integrase (IN) C-terminal domain
Structure domains: SH3 type barrels.
Length: 89 amino acids
Theoretical weight: 10.13 KDa
Source organism: Moloney murine leukemia virus isolate Shinnick
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P03355 (Residues: 1659-1738; Coverage: 5%)
Sequence domains: Murine leukemia virus (MLV) integrase (IN) C-terminal domain
Structure domains: SH3 type barrels.
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
Chemical shift assignment:
82%
Refinement method:
simulated annealing
Expression system: Escherichia coli BL21(DE3)
