› 2mn3

Solution NMR

Structure of Platypus 'Intermediate' Defensin-like Peptide (Int-DLP)

Released:
DOI: 10.2210/pdb2mn3/pdb
PDB entry 2mn3 coloured by chain, ensemble of 20 models, front view.
PDB entry 2mn3 coloured by chain, ensemble of 20 models, side view.
PDB entry 2mn3 coloured by chain, ensemble of 20 models, top view.
Source organism: Ornithorhynchus anatinus
Primary publication:
Structure and antimicrobial activity of platypus 'intermediate' defensin-like peptide.
Torres AM, Bansal P, Koh JM, Pagès G, Wu MJ, Kuchel PW
FEBS Lett 588 1821-6 (2014)
PMID: 24694388

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-533646 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Venom-like beta-defensin Chain: A
Molecule details ›
Chain: A
Length: 44 amino acids
Theoretical weight: 5 KDa
Source organism: Ornithorhynchus anatinus
Expression system: Not provided
UniProt:
  • Canonical: P0C8B1 (Residues: 25-68; Coverage: 100%)
Sequence domains: Platypus intermediate defensin-like peptide
Structure domains: Anthopleurin-A

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 42%
Refinement method: DGSA-distance geometry simulated annealing
Expression system: Not provided

Quick links

Citations

1 review citation

Mammals' humoral immune proteins and peptides targeting the bacterial envelope: from natural protection to therapeutic applications against multidrug-resistant Gram-negatives.
Escobar-Salom et al. (2022)
2 other articles