› 2mni

Solution NMR

Chemical Shift Assignments and structure of Q4D059, a hypothetical protein from Trypanosoma cruzi

Released:
DOI: 10.2210/pdb2mni/pdb
PDB entry 2mni coloured by chain, ensemble of 20 models, front view.
PDB entry 2mni coloured by chain, ensemble of 20 models, side view.
PDB entry 2mni coloured by chain, ensemble of 20 models, top view.
Source organism: Trypanosoma cruzi
Primary publication:
NMR structure and dynamics of Q4D059, a kinetoplastid-specific and conserved protein from Trypanosoma cruzi.
López-Castilla A, Pons T, Pires JR
J Struct Biol 190 11-20 (2015)
PMID: 25748338

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-175454 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
HP_Q4D059 Chain: A
Molecule details ›
Chain: A
Length: 92 amino acids
Theoretical weight: 10.43 KDa
Source organism: Trypanosoma cruzi
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q4D059 (Residues: 1-86; Coverage: 100%)
Gene name: Tc00.1047053510347.29
Sequence domains: Hypothetical protein Q4D059-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 78%
Refinement method: simulated annealing, torsion angle dynamics, water refinement
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 citations in other articles

Mutations in MAP3K1 that cause 46,XY disorders of sex development disrupt distinct structural domains in the protein.
Chamberlin et al. (2019)

1 mention without citation

A new approach to study semi-coordination using two 2-methyl-5-nitroimidazole copper(ii) complexes of biological interest as a model system.
Fachini et al. (2023)