› 2mpe

Solution NMR

Solution NMR structure for B. pseudomallei BPSL1050

Released:
DOI: 10.2210/pdb2mpe/pdb
PDB entry 2mpe coloured by chain, ensemble of 15 models, front view.
PDB entry 2mpe coloured by chain, ensemble of 15 models, side view.
PDB entry 2mpe coloured by chain, ensemble of 15 models, top view.
Source organism: Burkholderia pseudomallei K96243
Primary publication:
Structure-based design of a B cell antigen from B. pseudomallei.
Gaudesi D, Peri C, Quilici G, Gori A, Ferrer-Navarro M, Conchillo-Solé O, Thomas R, Nithichanon A, Lertmemongkolchai G, Titball R, Daura X, Colombo G, Musco G
ACS Chem Biol 10 803-12 (2015)
PMID: 25495888

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-179096 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DUF5594 domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 130 amino acids
Theoretical weight: 14.26 KDa
Source organism: Burkholderia pseudomallei K96243
Expression system: Escherichia coli
UniProt:
  • Canonical: Q63W39 (Residues: 1-126; Coverage: 100%)
Gene name: BPSL1050
Sequence domains: Domain of unknown function (DUF5594)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 77%
Refinement method: simulated annealing, torsion angle dynamics
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Burkholderia pseudomallei and Burkholderia mallei vaccines: Are we close to clinical trials?
Titball et al. (2017)
2 more

1 mention without citation

Evolving serodiagnostics by rationally designed peptide arrays: the Burkholderia paradigm in Cystic Fibrosis.
Peri et al. (2016)