Function and Biology Details
Reaction catalysed:
(1a) S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [HECT-type E3 ubiquitin transferase]-L-cysteine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + S-ubiquitinyl-[HECT-type E3 ubiquitin transferase]-L-cysteine
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assemblies composition:
Assembly name:
PDBe Complex ID:
PDB-CPX-129551 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Rho guanine nucleotide exchange factor 7
Molecule details ›
Chain: A
Length: 59 amino acids
Theoretical weight: 6.73 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Variant SH3 domain
Structure domains: SH3 Domains
Length: 59 amino acids
Theoretical weight: 6.73 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
O55043 (Residues: 10-63; Coverage: 8%)
Sequence domains: Variant SH3 domain
Structure domains: SH3 Domains
E3 ubiquitin-protein ligase Itchy homolog
Molecule details ›
Chain: T
Length: 25 amino acids
Theoretical weight: 2.7 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Length: 25 amino acids
Theoretical weight: 2.7 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical: Q96J02 (Residues: 246-270; Coverage: 3%)
