2pon

Solution NMR

Solution structure of the Bcl-xL/Beclin-1 complex

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-170520 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Beclin-1 Chain: A
Molecule details ›
Chain: A
Length: 23 amino acids
Theoretical weight: 2.5 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q14457 (Residues: 106-128; Coverage: 5%)
Gene names: BECN1, GT197
Sequence domains: Beclin-1 BH3 domain, Bcl-2-interacting
Bcl-2-like protein 1 Chain: B
Molecule details ›
Chain: B
Length: 156 amino acids
Theoretical weight: 17.9 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q07817 (Residues: 1-196; Coverage: 67%)
Gene names: BCL2L, BCL2L1, BCLX
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Escherichia coli