› 2qq9

X-ray diffraction
1.71Å resolution

Crystal Structure of DtxR(D6A C102D) Complexed with Nickel(II)

Released:
DOI: 10.2210/pdb2qq9/pdb
PDB entry 2qq9 coloured by chain, front view.
PDB entry 2qq9 coloured by chain, side view.
PDB entry 2qq9 coloured by chain, top view.
Source organism: Corynebacterium diphtheriae
Primary publication:
Role of the N-terminal helix in the metal ion-induced activation of the diphtheria toxin repressor DtxR.
D'Aquino JA, Lattimer JR, Denninger A, D'Aquino KE, Ringe D
Biochemistry 46 11761-70 (2007)
PMID: 17902703

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-534085 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Diphtheria toxin repressor Chain: A
Molecule details ›
Chain: A
Length: 226 amino acids
Theoretical weight: 25.32 KDa
Source organism: Corynebacterium diphtheriae
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P0DJL7 (Residues: 1-226; Coverage: 100%)
Gene names: DIP1414, dtxR
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand NI 2 x NI
Ligand PO4 1 x PO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: OXFORD DIFFRACTION ENHANCE ULTRA
Spacegroup: P3121
Unit cell:
a: 62.711Å b: 62.711Å c: 107.414Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.239 0.236 0.291
Expression system: Escherichia coli BL21(DE3)

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Citations

2 review citations

Coordination chemistry of bacterial metal transport and sensing.
Ma et al. (2009)
1 more