› 2rq8

Solution NMR

Solution NMR structure of titin I27 domain mutant

Released:
DOI: 10.2210/pdb2rq8/pdb
PDB entry 2rq8 coloured by chain, ensemble of 20 models, front view.
PDB entry 2rq8 coloured by chain, ensemble of 20 models, side view.
PDB entry 2rq8 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Structural basis for unfolding pathway-dependent stability of proteins: vectorial unfolding versus global unfolding.
Yagawa K, Yamano K, Oguro T, Maeda M, Sato T, Momose T, Kawano S, Endo T
Protein Sci 19 693-702 (2010)
PMID: 20095049

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-186809 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Titin Chain: A
Molecule details ›
Chain: A
Length: 98 amino acids
Theoretical weight: 10.93 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8WZ42 (Residues: 12677-12765; Coverage: 0%)
Gene name: TTN
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Structure of giant muscle proteins.
Meyer et al. (2013)
11 other articles

1 mention without citation

Structural basis for unfolding pathway-dependent stability of proteins: vectorial unfolding versus global unfolding.
Yagawa et al. (2010)