2y7q

X-ray diffraction
3.4Å resolution

THE HIGH-AFFINITY COMPLEX BETWEEN IGE AND ITS RECEPTOR FC EPSILON RI

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-134794 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
High affinity immunoglobulin epsilon receptor subunit alpha Chain: A
Molecule details ›
Chain: A
Length: 188 amino acids
Theoretical weight: 21.72 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P12319 (Residues: 26-209; Coverage: 77%)
Gene names: FCE1A, FCER1A
Sequence domains:
Structure domains: Immunoglobulins
Immunoglobulin heavy constant epsilon Chains: B, D
Molecule details ›
Chains: B, D
Length: 327 amino acids
Theoretical weight: 36.35 KDa
Source organism: Homo sapiens
Expression system: Mus musculus
UniProt:
  • Canonical: P01854 (Residues: 104-427; Coverage: 59%)
  • Best match: P01854-1 (Residues: 104-428)
Gene name: IGHE
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P212121
Unit cell:
a: 99.491Å b: 103.341Å c: 110.122Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.248 0.245 0.292
Expression systems:
  • Homo sapiens
  • Mus musculus