Function and Biology

Normal mode-based flexible fitted coordinates of a non-translocating SecYEG protein-conducting channel into the cryo-EM map of a SecYEG-nascent chain-70S ribosome complex from E. coli

Source organism: Escherichia coli
Biochemical function: protein transmembrane transporter activity
Biological process: intracellular protein transport
Cellular component: membrane

GO terms

Sequence families

Pfam Protein families (Pfam)
PF00584
Domain description: SecE/Sec61-gamma subunits of protein translocation complex
Occurring in:
  1. Protein translocase subunit SecE
The deposited structure of PDB entry 2akh contains 2 copies of Pfam domain PF00584 (SecE/Sec61-gamma subunits of protein translocation complex) in Protein translocase subunit SecE. Showing 1 copy in chain F [auth C].

PF00344
Domain description: SecY
Occurring in:
  1. Protein translocase subunit SecY
The deposited structure of PDB entry 2akh contains 2 copies of Pfam domain PF00344 (SecY) in Protein translocase subunit SecY. Showing 1 copy in chain E [auth B].

PF03840
Domain description: Preprotein translocase SecG subunit
Occurring in:
  1. Protein-export membrane protein SecG
The deposited structure of PDB entry 2akh contains 2 copies of Pfam domain PF03840 (Preprotein translocase SecG subunit) in Protein-export membrane protein SecG. Showing 1 copy in chain D [auth A].

InterPro InterPro annotations
IPR004692
Domain description: Preprotein translocase SecG subunit
Occurring in:
  1. Protein-export membrane protein SecG
IPR005807
Domain description: SecE subunit of protein translocation complex, bacterial-like
Occurring in:
  1. Protein translocase subunit SecE
IPR002208
Domain description: SecY/SEC61-alpha family
Occurring in:
  1. Protein translocase subunit SecY
IPR001901
Domain description: Protein translocase complex, SecE/Sec61-gamma subunit
Occurring in:
  1. Protein translocase subunit SecE
IPR030659
Domain description: SecY conserved site
Occurring in:
  1. Protein translocase subunit SecY
IPR023201
Domain description: SecY domain superfamily
Occurring in:
  1. Protein translocase subunit SecY
IPR038379
Domain description: SecE superfamily
Occurring in:
  1. Protein translocase subunit SecE
IPR026593
Domain description: Protein translocase subunit SecY
Occurring in:
  1. Protein translocase subunit SecY