2arw

Solution NMR

The solution structure of the membrane proximal cytokine receptor domain of the human interleukin-6 receptor

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-530924 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Soluble interleukin-6 receptor subunit alpha Chain: A
Molecule details ›
Chain: A
Length: 126 amino acids
Theoretical weight: 14.68 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P08887 (Residues: 212-336; Coverage: 28%)
Gene name: IL6R
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 51%
Refinement method: torsion angle dynamicsu
Expression system: Escherichia coli BL21