› 2av3

X-ray diffraction
1.7Å resolution

F97L- no ligand

Released:
DOI: 10.2210/pdb2av3/pdb
PDB entry 2av3 coloured by chain, front view.
PDB entry 2av3 coloured by chain, side view.
PDB entry 2av3 coloured by chain, top view.
Source organism: Anadara inaequivalvis
Primary publication:
Residue F4 plays a key role in modulating oxygen affinity and cooperativity in Scapharca dimeric hemoglobin.
Knapp JE, Bonham MA, Gibson QH, Nichols JC, Royer WE
Biochemistry 44 14419-30 (2005)
PMID: 16262242

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-135420 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Globin-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 146 amino acids
Theoretical weight: 15.93 KDa
Source organism: Anadara inaequivalvis
Expression system: Escherichia coli
UniProt:
  • Canonical: P02213 (Residues: 1-146; Coverage: 100%)
Sequence domains: Globin
Structure domains: Globins

Ligands and Environments

1 bound ligand:
Ligand HEM 2 x HEM
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: C2221
Unit cell:
a: 91.99Å b: 44.27Å c: 143.83Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.191 0.184 0.2
Expression system: Escherichia coli

Quick links

Citations

5 review citations

Simulations of allosteric transitions.
Elber R. (2011)
4 more