› 2bc8

Solution NMR

[Sec2,3,8,12]-ImI

Released:
DOI: 10.2210/pdb2bc8/pdb
PDB entry 2bc8 coloured by chain, ensemble of 20 models, front view.
PDB entry 2bc8 coloured by chain, ensemble of 20 models, side view.
PDB entry 2bc8 coloured by chain, ensemble of 20 models, top view.
Source organism: Conus imperialis
Primary publication:
Alpha-selenoconotoxins, a new class of potent alpha7 neuronal nicotinic receptor antagonists.
Armishaw CJ, Daly NL, Nevin ST, Adams DJ, Craik DJ, Alewood PF
J Biol Chem 281 14136-43 (2006)
PMID: 16500898

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156277 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alpha-conotoxin ImI Chain: A
Molecule details ›
Chain: A
Length: 12 amino acids
Theoretical weight: 1.55 KDa
Source organism: Conus imperialis
Expression system: Not provided
UniProt:
  • Canonical: P50983 (Residues: 5-16; Coverage: 71%)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Not provided

Quick links

Citations

23 review citations

Venoms as a platform for human drugs: translating toxins into therapeutics.
King GF. (2011)
22 more

1 mention without citation

Discovery, synthesis, and structure-activity relationships of conotoxins.
Akondi et al. (2014)