Function and Biology

Kap95p:RanGTP complex

Sequence families

Pfam Protein families (Pfam)
PF02985
Domain description: HEAT repeat
Occurring in:
  1. Importin subunit beta-1
The deposited structure of PDB entry 2bku contains 2 copies of Pfam domain PF02985 (HEAT repeat) in Importin subunit beta-1. Showing 1 copy in chain B.

PF03810
Domain description: Importin-beta N-terminal domain
Occurring in:
  1. Importin subunit beta-1
The deposited structure of PDB entry 2bku contains 2 copies of Pfam domain PF03810 (Importin-beta N-terminal domain) in Importin subunit beta-1. Showing 1 copy in chain B.

PF00071
Domain description: Ras family
Occurring in:
  1. GTP-binding nuclear protein Ran
The deposited structure of PDB entry 2bku contains 2 copies of Pfam domain PF00071 (Ras family) in GTP-binding nuclear protein Ran. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR002041
Domain description: Ran GTPase
Occurring in:
  1. GTP-binding nuclear protein Ran
IPR001806
Domain description: Small GTPase
Occurring in:
  1. GTP-binding nuclear protein Ran
IPR000225
Domain description: Armadillo
Occurring in:
  1. Importin subunit beta-1
IPR001494
Domain description: Importin-beta, N-terminal domain
Occurring in:
  1. Importin subunit beta-1
IPR027417
Domain description: P-loop containing nucleoside triphosphate hydrolase
Occurring in:
  1. GTP-binding nuclear protein Ran
IPR021133
Domain description: HEAT, type 2
Occurring in:
  1. Importin subunit beta-1
IPR040122
Domain description: Importin beta family
Occurring in:
  1. Importin subunit beta-1
IPR011989
Domain description: Armadillo-like helical
Occurring in:
  1. Importin subunit beta-1
IPR016024
Domain description: Armadillo-type fold
Occurring in:
  1. Importin subunit beta-1
IPR005225
Domain description: Small GTP-binding domain
Occurring in:
  1. GTP-binding nuclear protein Ran

Structure domains

CATH CATH domains
1.25.10.10
Class: Mainly Alpha
Architecture: Alpha Horseshoe
Topology: Leucine-rich Repeat Variant
Homology: Leucine-rich Repeat Variant
Occurring in:
  1. Importin subunit beta-1
The deposited structure of PDB entry 2bku contains 2 copies of CATH domain 1.25.10.10 (Leucine-rich Repeat Variant) in Importin subunit beta-1. Showing 1 copy in chain B.
3.40.50.300
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Rossmann fold
Homology: P-loop containing nucleotide triphosphate hydrolases
Occurring in:
  1. GTP-binding nuclear protein Ran
The deposited structure of PDB entry 2bku contains 2 copies of CATH domain 3.40.50.300 (Rossmann fold) in GTP-binding nuclear protein Ran. Showing 1 copy in chain A.
SCOP SCOP annotation
48372
Class: All alpha proteins
Fold: alpha-alpha superhelix
Superfamily: ARM repeat
Occurring in:
  1. Importin subunit beta-1
The deposited structure of PDB entry 2bku contains 2 copies of SCOP domain 48372 (Armadillo repeat) in Importin subunit beta-1. Showing 1 copy in chain B.