Function and Biology

Nup50:importin-alpha complex

Source organism: Mus musculus
Biochemical function: not assigned
Biological process: not assigned
Cellular component: nuclear pore

GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF00514
Domain description: Armadillo/beta-catenin-like repeat
Occurring in:
  1. Importin subunit alpha-1
The deposited structure of PDB entry 2c1m contains 7 copies of Pfam domain PF00514 (Armadillo/beta-catenin-like repeat) in Importin subunit alpha-1. Showing 7 copies in chain A.

PF08911
Domain description: NUP50 (Nucleoporin 50 kDa)
Occurring in:
  1. Nuclear pore complex protein Nup50
The deposited structure of PDB entry 2c1m contains 1 copy of Pfam domain PF08911 (NUP50 (Nucleoporin 50 kDa)) in Nuclear pore complex protein Nup50. Showing 1 copy in chain B.

PF16186
Domain description: Atypical Arm repeat
Occurring in:
  1. Importin subunit alpha-1
The deposited structure of PDB entry 2c1m contains 1 copy of Pfam domain PF16186 (Atypical Arm repeat ) in Importin subunit alpha-1. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR000225
Domain description: Armadillo
Occurring in:
  1. Importin subunit alpha-1
IPR015007
Domain description: Nuclear pore complex, NUP2/50/61
Occurring in:
  1. Nuclear pore complex protein Nup50
IPR032413
Domain description: Atypical Arm repeat
Occurring in:
  1. Importin subunit alpha-1
IPR016024
Domain description: Armadillo-type fold
Occurring in:
  1. Importin subunit alpha-1
IPR011989
Domain description: Armadillo-like helical
Occurring in:
  1. Importin subunit alpha-1

Structure domain

CATH CATH domain
1.25.10.10
Class: Mainly Alpha
Architecture: Alpha Horseshoe
Topology: Leucine-rich Repeat Variant
Homology: Leucine-rich Repeat Variant
Occurring in:
  1. Importin subunit alpha-1
The deposited structure of PDB entry 2c1m contains 1 copy of CATH domain 1.25.10.10 (Leucine-rich Repeat Variant) in Importin subunit alpha-1. Showing 1 copy in chain A.