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Structural basis of the nucleotide driven conformational changes in the AAA domain of transcription activator PspF

Source organism: Escherichia coli K-12
Biochemical function: ATP hydrolysis activity
Biological process: regulation of DNA-templated transcription
Cellular component: not assigned

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GO terms

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF00158
Domain description: Sigma-54 interaction domain
Occurring in:
  1. Psp operon transcriptional activator
The deposited structure of PDB entry 2c99 contains 1 copy of Pfam domain PF00158 (Sigma-54 interaction domain) in Psp operon transcriptional activator. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR002078
Domain description: RNA polymerase sigma factor 54 interaction domain
Occurring in:
  1. Psp operon transcriptional activator
IPR027417
Domain description: P-loop containing nucleoside triphosphate hydrolase
Occurring in:
  1. Psp operon transcriptional activator
IPR025944
Domain description: Sigma-54 interaction domain, conserved site
Occurring in:
  1. Psp operon transcriptional activator
IPR025943
Domain description: Sigma-54 interaction domain, ATP-binding site 2
Occurring in:
  1. Psp operon transcriptional activator
IPR003593
Domain description: AAA+ ATPase domain
Occurring in:
  1. Psp operon transcriptional activator
IPR014317
Domain description: Transcription activator PspF
Occurring in:
  1. Psp operon transcriptional activator

Structure domains

CATH CATH domains
1.10.8.60
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Helicase, Ruva Protein; domain 3
Homology: Helicase, Ruva Protein; domain 3
Occurring in:
  1. Psp operon transcriptional activator
The deposited structure of PDB entry 2c99 contains 1 copy of CATH domain 1.10.8.60 (Helicase, Ruva Protein; domain 3) in Psp operon transcriptional activator. Showing 1 copy in chain A.
3.40.50.300
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Rossmann fold
Homology: P-loop containing nucleotide triphosphate hydrolases
Occurring in:
  1. Psp operon transcriptional activator
The deposited structure of PDB entry 2c99 contains 1 copy of CATH domain 3.40.50.300 (Rossmann fold) in Psp operon transcriptional activator. Showing 1 copy in chain A.

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