› 2chd

X-ray diffraction
1.92Å resolution

Crystal structure of the C2A domain of Rabphilin-3A

Released:
DOI: 10.2210/pdb2chd/pdb
PDB entry 2chd coloured by chain, front view.
PDB entry 2chd coloured by chain, side view.
PDB entry 2chd coloured by chain, top view.
Source organism: Rattus norvegicus
Primary publication:
Structure of the C2A domain of rabphilin-3A.
Biadene M, Montaville P, Sheldrick GM, Becker S
Acta Crystallogr D Biol Crystallogr 62 793-9 (2006)
PMID: 16790935

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-155637 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Rabphilin-3A Chain: A
Molecule details ›
Chain: A
Length: 142 amino acids
Theoretical weight: 16.22 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P47709 (Residues: 371-510; Coverage: 21%)
Gene name: Rph3a
Sequence domains: C2 domain
Structure domains: C2 domain

Ligands and Environments

1 bound ligand:
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BRUKER ROTATING ANODE
Spacegroup: P212121
Unit cell:
a: 37.87Å b: 39.16Å c: 88.85Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.201 0.198 0.269
Expression system: Escherichia coli BL21

Quick links

Citations

2 review citations

Signaling through C2 domains: more than one lipid target.
Corbalan-Garcia et al. (2014)
1 more

3 mentions without citation

Structural insights into the Ca2+ and PI(4,5)P2 binding modes of the C2 domains of rabphilin 3A and synaptotagmin 1.
Guillén et al. (2013)
2 more