› 2cjr

X-ray diffraction
2.5Å resolution

Crystal structure of oligomerization domain of SARS coronavirus nucleocapsid protein.

Released:
DOI: 10.2210/pdb2cjr/pdb
Model geometry
Fit model/data
PDB entry 2cjr coloured by chain, front view.
PDB entry 2cjr coloured by chain, side view.
PDB entry 2cjr coloured by chain, top view.
Source organism: SARS coronavirus TW1
Primary publication:
Structure of the SARS coronavirus nucleocapsid protein RNA-binding dimerization domain suggests a mechanism for helical packaging of viral RNA.
Chen CY, Chang CK, Chang YW, Sue SC, Bai HI, Riang L, Hsiao CD, Huang TH
OpenAccess logo J Mol Biol 368 1075-86 (2007)
PMID: 17379242

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157823 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nucleoprotein Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 128 amino acids
Theoretical weight: 14.56 KDa
Source organism: SARS coronavirus TW1
Expression system: Escherichia coli
UniProt:
  • Canonical: P59595 (Residues: 248-365; Coverage: 28%)
Gene names: 9a, N
Sequence domains: Coronavirus nucleocapsid

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: SPRING-8 BEAMLINE BL12B2
Spacegroup: C2
Unit cell:
a: 159.423Å b: 84.203Å c: 105.177Å
α: 90° β: 131.18° γ: 90°
R-values:
R R work R free
0.256 0.256 0.269
Expression system: Escherichia coli

Quick links

Citations

32 review citations

The coronavirus nucleocapsid is a multifunctional protein.
McBride et al. (2014)
31 more

32 mentions without citation

The SARS coronavirus nucleocapsid protein--forms and functions.
Chang et al. (2014)
31 more