Function and Biology Details
Reaction catalysed:
S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150612 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Polycomb complex protein BMI-1
Molecule details ›
Chain: A
Length: 108 amino acids
Theoretical weight: 12.53 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
Sequence domains: Zinc finger, C3HC4 type (RING finger)
Structure domains: Zinc/RING finger domain, C3HC4 (zinc finger)
Length: 108 amino acids
Theoretical weight: 12.53 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
- Canonical:
P25916 (Residues: 1-108; Coverage: 33%)
Sequence domains: Zinc finger, C3HC4 type (RING finger)
Structure domains: Zinc/RING finger domain, C3HC4 (zinc finger)
E3 ubiquitin-protein ligase RING2
Molecule details ›
Chain: B
Length: 165 amino acids
Theoretical weight: 18.73 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
Sequence domains: Zinc finger, C3HC4 type (RING finger)
Structure domains: Zinc/RING finger domain, C3HC4 (zinc finger)
Length: 165 amino acids
Theoretical weight: 18.73 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
- Canonical: Q9CQJ4 (Residues: 1-159; Coverage: 47%)
Sequence domains: Zinc finger, C3HC4 type (RING finger)
Structure domains: Zinc/RING finger domain, C3HC4 (zinc finger)
