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Crystal structure of mouse AMF / M6P complex

X-ray diffraction
1.65Å resolution
PDB entry 2cxu coloured by chain, front view.
PDB entry 2cxu coloured by chain, side view.
PDB entry 2cxu coloured by chain, top view.
Source organism: Mus musculus
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Glucose-6-phosphate isomerase
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Multimeric state: homo dimer
Accessible surface area: 37037.87 Å2
Buried surface area: 14308.73 Å2
Dissociation area: 6,669.9 Å2
Dissociation energy (ΔGdiss): 98.31 kcal/mol
Dissociation entropy (TΔSdiss): 16.52 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-529785

Macromolecules

Glucose-6-phosphate isomerase
Chains: A, B
Length: 557 amino acids
Theoretical weight: 62.69 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P06745 (Residues: 1-557; Coverage: 100%)
Gene names: Gpi, Gpi1
Pfam: Phosphoglucose isomerase
InterPro:
CATH:
Glucose-6-phosphate isomerase in PDB entry 2cxu, assembly 1, front view.
Glucose-6-phosphate isomerase in PDB entry 2cxu, assembly 1, side view.
Glucose-6-phosphate isomerase in PDB entry 2cxu, assembly 1, top view.
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