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Crystal structure of archeal RNase P protein ph1481p in complex with ph1877p

Source organism: Pyrococcus horikoshii
Biochemical function: protein binding
Biological process: tRNA processing
Cellular component: ribonuclease P complex

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EC 3.1.26.5: Ribonuclease P

Reaction catalysed:
Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.
Systematic name:
-
Alternative Name(s):
  • RNase P

GO terms

Sequence families

Pfam Protein families (Pfam)
PF01900
Domain description: Rpp14/Pop5 family
Occurring in:
  1. Ribonuclease P protein component 2
The deposited structure of PDB entry 2czv contains 2 copies of Pfam domain PF01900 (Rpp14/Pop5 family) in Ribonuclease P protein component 2. Showing 1 copy in chain D.

PF01876
Domain description: RNase P subunit p30
Occurring in:
  1. Ribonuclease P protein component 3
The deposited structure of PDB entry 2czv contains 2 copies of Pfam domain PF01876 (RNase P subunit p30) in Ribonuclease P protein component 3. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR002759
Domain description: RNase P subunit Pop5/Rpp14/Rnp2-like
Occurring in:
  1. Ribonuclease P protein component 2
IPR038085
Domain description: RNase P subunit Pop5/Rpp14/Rnp2-like domain superfamily
Occurring in:
  1. Ribonuclease P protein component 2
IPR016434
Domain description: Ribonuclease P protein subunit Rnp2, archaea
Occurring in:
  1. Ribonuclease P protein component 2
IPR002738
Domain description: RNase P subunit p30
Occurring in:
  1. Ribonuclease P protein component 3
IPR016195
Domain description: Polymerase/histidinol phosphatase-like
Occurring in:
  1. Ribonuclease P protein component 3
IPR023539
Domain description: Ribonuclease P, protein component 3, archaeal
Occurring in:
  1. Ribonuclease P protein component 3

Structure domains

CATH CATH domains
3.30.70.3250
Class: Alpha Beta
Architecture: 2-Layer Sandwich
Topology: Alpha-Beta Plaits
Homology: Ribonuclease P, Pop5 subunit
Occurring in:
  1. Ribonuclease P protein component 2
The deposited structure of PDB entry 2czv contains 2 copies of CATH domain 3.30.70.3250 (Alpha-Beta Plaits) in Ribonuclease P protein component 2. Showing 1 copy in chain D.
3.20.20.140
Class: Alpha Beta
Architecture: Alpha-Beta Barrel
Topology: TIM Barrel
Homology: Metal-dependent hydrolases
Occurring in:
  1. Ribonuclease P protein component 3
The deposited structure of PDB entry 2czv contains 2 copies of CATH domain 3.20.20.140 (TIM Barrel) in Ribonuclease P protein component 3. Showing 1 copy in chain A.
SCOP SCOP annotations
160351
Class: Alpha and beta proteins (a+b)
Fold: Ferredoxin-like
Superfamily: Rnp2-like
Occurring in:
  1. Ribonuclease P protein component 2
The deposited structure of PDB entry 2czv contains 2 copies of SCOP domain 160351 (Rpp14/Pop5-like) in Ribonuclease P protein component 2. Showing 1 copy in chain D.
110442
Class: Alpha and beta proteins (a/b)
Fold: 7-stranded beta/alpha barrel
Superfamily: PHP domain-like
Occurring in:
  1. Ribonuclease P protein component 3
The deposited structure of PDB entry 2czv contains 2 copies of SCOP domain 110442 (RNase P subunit p30) in Ribonuclease P protein component 3. Showing 1 copy in chain A.

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