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X-ray structure of the sucrose-phosphatase (SPP) from Synechocystis sp.PCC6803 in complex with maltose

Source organism: Synechocystis sp. PCC 6803
Biochemical function: sucrose-phosphate phosphatase activity
Biological process: sucrose biosynthetic process
Cellular component: not assigned

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EC 3.1.3.24: Sucrose-phosphate phosphatase

Reaction catalysed:
Sucrose 6(F)-phosphate + H(2)O = sucrose + phosphate
Systematic name:
Sucrose-6(F)-phosphate phosphohydrolase
Alternative Name(s):
  • SPP
  • Sucrose 6-phosphate hydrolase
  • Sucrose phosphatase
  • Sucrose-6-phosphatase
  • Sucrose-6-phosphate phosphatase
  • Sucrose-phosphate hydrolase
  • Sucrose-phosphate phosphohydrolase

GO terms

Sequence family

Pfam Protein family (Pfam)
PF05116
Domain description: Sucrose-6F-phosphate phosphohydrolase
Occurring in:
  1. sucrose-phosphate phosphatase
The deposited structure of PDB entry 2d2v contains 1 copy of Pfam domain PF05116 (Sucrose-6F-phosphate phosphohydrolase) in sucrose-phosphate phosphatase. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR023214
Domain description: HAD superfamily
Occurring in:
  1. sucrose-phosphate phosphatase
IPR006379
Domain description: HAD-superfamily hydrolase, subfamily IIB
Occurring in:
  1. sucrose-phosphate phosphatase
IPR036412
Domain description: HAD-like superfamily
Occurring in:
  1. sucrose-phosphate phosphatase
IPR012847
Domain description: Sucrose phosphatase, plant/cyanobacteria
Occurring in:
  1. sucrose-phosphate phosphatase
IPR006380
Domain description: Sucrose phosphatase-like domain
Occurring in:
  1. sucrose-phosphate phosphatase

Structure domains

CATH CATH domains
3.40.50.1000
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Rossmann fold
Homology: HAD superfamily/HAD-like
Occurring in:
  1. sucrose-phosphate phosphatase
The deposited structure of PDB entry 2d2v contains 1 copy of CATH domain 3.40.50.1000 (Rossmann fold) in sucrose-phosphate phosphatase. Showing 1 copy in chain A.
3.90.1070.10
Class: Alpha Beta
Architecture: Alpha-Beta Complex
Topology: Hypothetical Protein Ta0175; Chain: A, domain 2
Homology: Hypothetical Protein Ta0175; Chain: A, domain 2
Occurring in:
  1. sucrose-phosphate phosphatase
The deposited structure of PDB entry 2d2v contains 1 copy of CATH domain 3.90.1070.10 (Hypothetical Protein Ta0175; Chain: A, domain 2) in sucrose-phosphate phosphatase. Showing 1 copy in chain A.
SCOP SCOP annotation
82388
Class: Alpha and beta proteins (a/b)
Fold: HAD-like
Superfamily: HAD-like
Occurring in:
  1. sucrose-phosphate phosphatase
The deposited structure of PDB entry 2d2v contains 1 copy of SCOP domain 82388 (Predicted hydrolases Cof) in sucrose-phosphate phosphatase. Showing 1 copy in chain A.

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