EC 5.2.1.8: Peptidylprolyl isomerase
Reaction catalysed:
Peptidylproline (omega=180) = peptidylproline (omega=0)
Systematic name:
Peptidylproline cis-trans-isomerase
Alternative Name(s):
- Cyclophilin
- PPIase
- Peptide bond isomerase
- Peptidyl-prolyl cis-trans isomerase
- Peptidylprolyl cis-trans isomerase
- Rotamase
GO terms
Biochemical function:
Biological process:
Cellular component:
Sequence families
Protein families (Pfam)
RNA family (Rfam)
InterPro annotations
IPR012678
Domain description:
Ribosomal protein uL23/eL15/eS24 core domain superfamily
Occurring in:
Occurring in:
Structure domains
CATH domains
1.10.287.310
Class:
Mainly Alpha
Architecture:
Orthogonal Bundle
Topology:
Helix Hairpins
Homology:
Helix Hairpins
Occurring in:
3.30.70.330
Class:
Alpha Beta
Architecture:
2-Layer Sandwich
Topology:
Alpha-Beta Plaits
Homology:
Alpha-Beta Plaits
Occurring in:
SCOP annotations
46562
Class:
All alpha proteins
Fold:
Long alpha-hairpin
Superfamily:
Ribosomal protein L29 (L29p)
Occurring in:
50105
Class:
All beta proteins
Fold:
SH3-like barrel
Superfamily:
Translation proteins SH3-like domain
Occurring in:
54190
Class:
Alpha and beta proteins (a+b)
Fold:
Ribosomal proteins S24e, L23 and L15e
Superfamily:
Ribosomal proteins S24e, L23 and L15e
Occurring in: