Function and Biology Details
Reaction catalysed:
GTP + H(2)O = GDP + phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Translational (tr)-type GTP-binding domain
- Translation initiation factor IF2/IF5 domain
- Translation initiation factor 2, beta subunit
- Initiation factor eIF2 gamma, C-terminal
- Translation initiation factor 2, gamma subunit
- P-loop containing nucleoside triphosphate hydrolase
- Translation initiation factor IF2/IF5, zinc-binding
- Translation initiation factor IF2/IF5
7 more domains
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Translation initiation factor 2 (preferred)
PDBe Complex ID:
PDB-CPX-570336 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Translation initiation factor 2 subunit gamma
Molecule details ›
Chain: A
Length: 419 amino acids
Theoretical weight: 46.23 KDa
Source organism: Pyrococcus furiosus DSM 3638
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 419 amino acids
Theoretical weight: 46.23 KDa
Source organism: Pyrococcus furiosus DSM 3638
Expression system: Escherichia coli
UniProt:
- Canonical:
Q8U082 (Residues: 1-411; Coverage: 100%)
Sequence domains:
- Elongation factor Tu GTP binding domain
- Elongation factor Tu domain 2
- Initiation factor eIF2 gamma, C terminal
Translation initiation factor 2 subunit beta
Molecule details ›
Chain: B
Length: 148 amino acids
Theoretical weight: 17.33 KDa
Source organism: Pyrococcus furiosus DSM 3638
Expression system: Escherichia coli
UniProt:
Sequence domains: Domain found in IF2B/IF5
Structure domains: Alpha-Beta Plaits
Length: 148 amino acids
Theoretical weight: 17.33 KDa
Source organism: Pyrococcus furiosus DSM 3638
Expression system: Escherichia coli
UniProt:
- Canonical: Q8U3I5 (Residues: 1-140; Coverage: 100%)
Sequence domains: Domain found in IF2B/IF5
Structure domains: Alpha-Beta Plaits
