› › Function and Biology

Solution structure of the sam-domain of mouse phosphatidyl ceramidecholinephosphotransferase 1

Source organism: Mus musculus
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

Quick links

EC 2.7.8.27: Sphingomyelin synthase

Reaction catalysed:
A ceramide + a phosphatidylcholine = a sphingomyelin + a 1,2-diacyl-sn-glycerol
Systematic name:
Ceramide:phosphatidylcholine cholinephosphotransferase
Alternative Name(s):
  • Phosphatidylcholine:ceramide cholinephosphotransferase
  • SM synthase
  • SMS1
  • SMS2

GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

InterPro InterPro annotations
IPR013761
Domain description: Sterile alpha motif/pointed domain superfamily
Occurring in:
  1. Phosphatidylcholine:ceramide cholinephosphotransferase 1
IPR041418
Domain description: SAM domain
Occurring in:
  1. Phosphatidylcholine:ceramide cholinephosphotransferase 1
IPR001660
Domain description: Sterile alpha motif domain
Occurring in:
  1. Phosphatidylcholine:ceramide cholinephosphotransferase 1

Structure domain

CATH CATH domain
1.10.150.50
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: DNA polymerase; domain 1
Homology: Transcription Factor, Ets-1
Occurring in:
  1. Phosphatidylcholine:ceramide cholinephosphotransferase 1
The deposited structure of PDB entry 2d8c contains 1 copy of CATH domain 1.10.150.50 (DNA polymerase; domain 1) in Phosphatidylcholine:ceramide cholinephosphotransferase 1. Showing 1 copy in chain A.
SCOP SCOP annotation
47773
Class: All alpha proteins
Fold: SAM domain-like
Superfamily: SAM/Pointed domain
Occurring in:
  1. Phosphatidylcholine:ceramide cholinephosphotransferase 1
The deposited structure of PDB entry 2d8c contains 1 copy of SCOP domain 47773 (SAM (sterile alpha motif) domain) in Phosphatidylcholine:ceramide cholinephosphotransferase 1. Showing 1 copy in chain A.

Quick links