Function and Biology

Crystal structure of Uracil-DNA glycosylase in complex with AP:A containing DNA

Source organisms:
Biochemical function: deaminated base DNA N-glycosylase activity
Biological process: base-excision repair
Cellular component: not assigned

Sequence family

Pfam Protein family (Pfam)
PF03167
Domain description: Uracil DNA glycosylase superfamily
Occurring in:
  1. Type-5 uracil-DNA glycosylase
The deposited structure of PDB entry 2dem contains 1 copy of Pfam domain PF03167 (Uracil DNA glycosylase superfamily) in Type-5 uracil-DNA glycosylase. Showing 1 copy in chain C [auth A].

InterPro InterPro annotations
IPR036895
Domain description: Uracil-DNA glycosylase-like domain superfamily
Occurring in:
  1. Type-5 uracil-DNA glycosylase
IPR005122
Domain description: Uracil-DNA glycosylase-like
Occurring in:
  1. Type-5 uracil-DNA glycosylase
IPR044147
Domain description: Uracil DNA glycosylase family 5
Occurring in:
  1. Type-5 uracil-DNA glycosylase

Structure domain

CATH CATH domain
3.40.470.10
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Uracil-DNA Glycosylase, subunit E
Homology: Uracil-DNA glycosylase-like domain
Occurring in:
  1. Type-5 uracil-DNA glycosylase
The deposited structure of PDB entry 2dem contains 1 copy of CATH domain 3.40.470.10 (Uracil-DNA Glycosylase, subunit E) in Type-5 uracil-DNA glycosylase. Showing 1 copy in chain C [auth A].