› 2dgb

X-ray diffraction
2.1Å resolution

Structure of Thermus thermophilus PurS in the P21 Form

Released:
DOI: 10.2210/pdb2dgb/pdb
PDB entry 2dgb coloured by chain, front view.
PDB entry 2dgb coloured by chain, side view.
PDB entry 2dgb coloured by chain, top view.
Source organism: Thermus thermophilus
Entry authors: Yanai H, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
ATP + N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide + L-glutamine + H(2)O = ADP + phosphate + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + L-glutamate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-180838 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Phosphoribosylformylglycinamidine synthase subunit PurS Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 84 amino acids
Theoretical weight: 9.36 KDa
Source organism: Thermus thermophilus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q72II0 (Residues: 1-84; Coverage: 100%)
Gene names: TT_C1152, purS
Sequence domains: Phosphoribosylformylglycinamidine (FGAM) synthase
Structure domains: Phosphoribosylformylglycinamidine synthase subunit PurS

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 12 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU ULTRAX 18
Spacegroup: P21
Unit cell:
a: 40.693Å b: 90.125Å c: 51.507Å
α: 90° β: 111.51° γ: 90°
R-values:
R R work R free
0.209 0.209 0.244
Expression system: Escherichia coli

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