› 2dty

X-ray diffraction
2.65Å resolution

Crystal structure of basic winged bean lectin complexed with N-acetyl-D-galactosamine

Released:
DOI: 10.2210/pdb2dty/pdb
PDB entry 2dty coloured by chain, front view.
PDB entry 2dty coloured by chain, side view.
PDB entry 2dty coloured by chain, top view.
Source organism: Psophocarpus tetragonolobus
Primary publication:
Structural basis for the carbohydrate-specificity of basic winged-bean lectin and its differential affinity for Gal and GalNAc.
Kulkarni KA, Katiyar S, Surolia A, Vijayan M, Suguna K
Acta Crystallogr D Biol Crystallogr 62 1319-24 (2006)
PMID: 17057334

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127671 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (4 distinct):
Basic agglutinin Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 241 amino acids
Theoretical weight: 26.51 KDa
Source organism: Psophocarpus tetragonolobus
UniProt:
  • Canonical: O24313 (Residues: 2-242; Coverage: 100%)
Gene name: WBAI
Sequence domains: Legume lectin domain
Structure domains: Jelly Rolls

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, FUC
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, FUC, BMA
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, FUL
Carbohydrate polymer
3 bound ligands:
Ligand A2G 4 x A2G
Ligand MN 4 x MN
Ligand CA 4 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: P21212
Unit cell:
a: 157.725Å b: 91.864Å c: 73.549Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.196 0.196 0.239

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Citations

2 citation in other articles

Generation of blood group specificity: new insights from structural studies on the complexes of A- and B-reactive saccharides with basic winged bean agglutinin.
Kulkarni et al. (2007)
1 more