› 2dwx

X-ray diffraction
2.55Å resolution

Co-crystal Structure Analysis of GGA1-GAE with the WNSF motif

Released:
DOI: 10.2210/pdb2dwx/pdb
Model geometry
Fit model/data
PDB entry 2dwx coloured by chain, front view.
PDB entry 2dwx coloured by chain, side view.
PDB entry 2dwx coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Molecular basis for autoregulatory interaction between GAE domain and hinge region of GGA1.
Inoue M, Shiba T, Ihara K, Yamada Y, Hirano S, Kamikubo H, Kataoka M, Kawasaki M, Kato R, Nakayama K, Wakatsuki S
Traffic 8 904-13 (2007)
PMID: 17506864

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
hetero dimer (preferred)
monomeric
Assembly name:
PDBe Complex ID:
PDB-CPX-193828 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
ADP-ribosylation factor-binding protein GGA1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 133 amino acids
Theoretical weight: 14.89 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9UJY5 (Residues: 507-639; Coverage: 21%)
Gene name: GGA1
Sequence domains: Adaptin C-terminal domain
Structure domains: Immunoglobulin-like
ADP-ribosylation factor-binding protein GGA1 Chains: P, Q
Molecule details ›
Chains: P, Q
Length: 13 amino acids
Theoretical weight: 1.39 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q9UJY5 (Residues: 376-388; Coverage: 2%)
Gene name: GGA1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: PHOTON FACTORY BEAMLINE AR-NW12A
Spacegroup: P212121
Unit cell:
a: 48.22Å b: 69.62Å c: 184.967Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.241 0.238 0.287
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided

Quick links

Citations

2 review citations

Survey of the year 2007 commercial optical biosensor literature.
Rich et al. (2008)
1 more

PDB-REDO

The sliders below show the change in model quality between original PDB entry and the PDB-REDO entry

Model Geometry
 
 
Data not available
DNA/RNA Geometry
 
 
Data not available
Fit model/data
 
 
Data not available
PDB-REDO