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High resolution structure of T. maritima tRNase Z

Source organism: Thermotoga maritima
Biochemical function: metal ion binding
Biological process: not assigned
Cellular component: not assigned

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EC 3.1.26.11: tRNase Z

Reaction catalysed:
Endonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA precursor, generating 3' termini of tRNAs. A 3'-hydroxy group is left at the tRNA terminus and a 5'-phosphoryl group is left at the trailer molecule.
Systematic name:
-
Alternative Name(s):
  • 3 tRNase
  • 3' tRNase
  • RNase Z
  • tRNA 3 endonuclease
  • tRNase Z

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF12706
Domain description: Beta-lactamase superfamily domain
Occurring in:
  1. Metallo-beta-lactamase domain-containing protein
The deposited structure of PDB entry 2e7y contains 2 copies of Pfam domain PF12706 (Beta-lactamase superfamily domain) in Metallo-beta-lactamase domain-containing protein. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR036866
Domain description: Ribonuclease Z/Hydroxyacylglutathione hydrolase-like
Occurring in:
  1. Metallo-beta-lactamase domain-containing protein
IPR001279
Domain description: Metallo-beta-lactamase
Occurring in:
  1. Metallo-beta-lactamase domain-containing protein
IPR013470
Domain description: Ribonuclease Z, Thermotoga-type
Occurring in:
  1. Metallo-beta-lactamase domain-containing protein

Structure domain

CATH CATH domain
3.60.15.10
Class: Alpha Beta
Architecture: 4-Layer Sandwich
Topology: Metallo-beta-lactamase; Chain A
Homology: Ribonuclease Z/Hydroxyacylglutathione hydrolase-like
Occurring in:
  1. Metallo-beta-lactamase domain-containing protein
The deposited structure of PDB entry 2e7y contains 2 copies of CATH domain 3.60.15.10 (Metallo-beta-lactamase; Chain A) in Metallo-beta-lactamase domain-containing protein. Showing 1 copy in chain A.
SCOP SCOP annotation
143916
Class: Alpha and beta proteins (a+b)
Fold: Metallo-hydrolase/oxidoreductase
Superfamily: Metallo-hydrolase/oxidoreductase
Occurring in:
  1. Metallo-beta-lactamase domain-containing protein
The deposited structure of PDB entry 2e7y contains 2 copies of SCOP domain 143916 (RNase Z-like) in Metallo-beta-lactamase domain-containing protein. Showing 1 copy in chain A.

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