› › Function and Biology

Crystal structure of the ligand-free form of the flavin reductase component (HpaC) of 4-hydroxyphenylacetate 3-monooxygenase

Source organism: Thermus thermophilus HB8
Biochemical function: riboflavin reductase (NADPH) activity
Biological process: catabolic process
Cellular component: not assigned

Quick links

EC 1.5.1.36: Flavin reductase (NADH)

Reaction catalysed:
Reduced flavin + NAD(+) = flavin + NADH
Systematic name:
Flavin:NAD(+) oxidoreductase
Alternative Name(s):
  • Flavin:NADH oxidoreductase
  • NADH-dependent flavin reductase

GO terms

Sequence family

Pfam Protein family (Pfam)
PF01613
Domain description: Flavin reductase like domain
Occurring in:
  1. 4-hydroxyphenylacetate 3-monooxygenase, reductase component
The deposited structure of PDB entry 2ecr contains 2 copies of Pfam domain PF01613 (Flavin reductase like domain) in 4-hydroxyphenylacetate 3-monooxygenase, reductase component. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR002563
Domain description: Flavin reductase like domain
Occurring in:
  1. 4-hydroxyphenylacetate 3-monooxygenase, reductase component
IPR012349
Domain description: FMN-binding split barrel
Occurring in:
  1. 4-hydroxyphenylacetate 3-monooxygenase, reductase component

Structure domain

CATH CATH domain
2.30.110.10
Class: Mainly Beta
Architecture: Roll
Topology: Pnp Oxidase; Chain A
Homology: Electron Transport, Fmn-binding Protein; Chain A
Occurring in:
  1. 4-hydroxyphenylacetate 3-monooxygenase, reductase component
The deposited structure of PDB entry 2ecr contains 2 copies of CATH domain 2.30.110.10 (Pnp Oxidase; Chain A) in 4-hydroxyphenylacetate 3-monooxygenase, reductase component. Showing 1 copy in chain A.

Quick links