Function and Biology

Solution structures of the fn3 domain of human receptor-type tyrosine-protein phosphatase F

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

EC 3.1.3.48: Protein-tyrosine-phosphatase

Reaction catalysed:
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate
Systematic name:
Protein-tyrosine-phosphate phosphohydrolase
Alternative Name(s):
  • (Phosphotyrosine)protein phosphatase
  • PPT-phosphatase
  • PTP-phosphatase
  • PTPase
  • Phosphoprotein phosphatase (phosphotyrosine)
  • Phosphotyrosine histone phosphatase
  • Phosphotyrosine phosphatase
  • Phosphotyrosine protein phosphatase
  • Phosphotyrosylprotein phosphatase
  • Protein phosphotyrosine phosphatase
  • Tyrosine O-phosphate phosphatase
  • Tyrosylprotein phosphatase

GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF00041
Domain description: Fibronectin type III domain
Occurring in:
  1. Receptor-type tyrosine-protein phosphatase F
The deposited structure of PDB entry 2edx contains 1 copy of Pfam domain PF00041 (Fibronectin type III domain) in Receptor-type tyrosine-protein phosphatase F. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR003961
Domain description: Fibronectin type III
Occurring in:
  1. Receptor-type tyrosine-protein phosphatase F
IPR013783
Domain description: Immunoglobulin-like fold
Occurring in:
  1. Receptor-type tyrosine-protein phosphatase F
IPR036116
Domain description: Fibronectin type III superfamily
Occurring in:
  1. Receptor-type tyrosine-protein phosphatase F

Structure domain

CATH CATH domain
2.60.40.10
Class: Mainly Beta
Architecture: Sandwich
Topology: Immunoglobulin-like
Homology: Immunoglobulins
Occurring in:
  1. Receptor-type tyrosine-protein phosphatase F
The deposited structure of PDB entry 2edx contains 1 copy of CATH domain 2.60.40.10 (Immunoglobulin-like) in Receptor-type tyrosine-protein phosphatase F. Showing 1 copy in chain A.