› 2eo2

Solution NMR

Solution structure of the insertion region (510-573) of FTHFS domain from mouse methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like protein

Released:
DOI: 10.2210/pdb2eo2/pdb
PDB entry 2eo2 coloured by chain, ensemble of 20 models, front view.
PDB entry 2eo2 coloured by chain, ensemble of 20 models, side view.
PDB entry 2eo2 coloured by chain, ensemble of 20 models, top view.
Source organism: Mus musculus
Entry authors: Kurosaki C, Nagashima T, Yoshida M, Hayashi F, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
ATP + formate + tetrahydrofolate = ADP + phosphate + 10-formyltetrahydrofolate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-174870 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Monofunctional C1-tetrahydrofolate synthase, mitochondrial Chain: A
Molecule details ›
Chain: A
Length: 71 amino acids
Theoretical weight: 7.9 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
  • Canonical: Q3V3R1 (Residues: 510-573; Coverage: 7%)
Gene names: Fthfsdc1, Mthfd1l
Structure domains: Helicase, Ruva Protein; domain 3

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Not provided

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