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Ubiquitin-Like Domain of Human Nuclear Zinc Finger Protein NP95

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

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EC 2.3.2.27: RING-type E3 ubiquitin transferase

Reaction catalysed:
S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine
Systematic name:
[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine:[acceptor protein]-L-lysine ubiquitin transferase (isopeptide bond-forming; RING-type)
Alternative Name(s):
  • RING E3 ligase
  • Ubiquitin transferase RING E3

GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF00240
Domain description: Ubiquitin family
Occurring in:
  1. E3 ubiquitin-protein ligase UHRF1
The deposited structure of PDB entry 2faz contains 2 copies of Pfam domain PF00240 (Ubiquitin family) in E3 ubiquitin-protein ligase UHRF1. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR000626
Domain description: Ubiquitin-like domain
Occurring in:
  1. E3 ubiquitin-protein ligase UHRF1
IPR029071
Domain description: Ubiquitin-like domain superfamily
Occurring in:
  1. E3 ubiquitin-protein ligase UHRF1

Structure domain

CATH CATH domain
3.10.20.90
Class: Alpha Beta
Architecture: Roll
Topology: Ubiquitin-like (UB roll)
Homology: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
Occurring in:
  1. E3 ubiquitin-protein ligase UHRF1
The deposited structure of PDB entry 2faz contains 2 copies of CATH domain 3.10.20.90 (Ubiquitin-like (UB roll)) in E3 ubiquitin-protein ligase UHRF1. Showing 1 copy in chain A.
SCOP SCOP annotation
54237
Class: Alpha and beta proteins (a+b)
Fold: beta-Grasp (ubiquitin-like)
Superfamily: Ubiquitin-like
Occurring in:
  1. E3 ubiquitin-protein ligase UHRF1
The deposited structure of PDB entry 2faz contains 2 copies of SCOP domain 54237 (Ubiquitin-related) in E3 ubiquitin-protein ligase UHRF1. Showing 1 copy in chain A.

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