› 2g2r

X-ray diffraction
2.75Å resolution

Green-fluorescent antibody 11G10 in complex with its hapten (nitro-stilbene derivative)

Released:
DOI: 10.2210/pdb2g2r/pdb
PDB entry 2g2r coloured by chain, front view.
PDB entry 2g2r coloured by chain, side view.
PDB entry 2g2r coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
The effects of antibodies on stilbene excited-state energetics.
Tian F, Debler EW, Millar DP, Deniz AA, Wilson IA, Schultz PG
Angew Chem Int Ed Engl 45 7763-5 (2006)
PMID: 17089439

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
hetero dimer (preferred)
hetero tetramer
Assembly name:
PDBe Complex ID:
PDB-CPX-211533 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Green-fluorescent antibody (11G10)-light chain Chains: A, L
Molecule details ›
Chains: A, L
Length: 219 amino acids
Theoretical weight: 24.2 KDa
Source organism: Mus musculus
Structure domains: Immunoglobulins
Ig heavy chain Mem5 Chains: B, H
Molecule details ›
Chains: B, H
Length: 219 amino acids
Theoretical weight: 23.68 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P84751 (Residues: 1-221; Coverage: 92%)
Sequence domains:
Structure domains: Immunoglobulins

Ligands and Environments

2 bound ligands:
Ligand SO4 3 x SO4
Ligand TNS 2 x TNS
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: C2
Unit cell:
a: 164.788Å b: 53.761Å c: 110.39Å
α: 90° β: 94.64° γ: 90°
R-values:
R R work R free
0.205 0.203 0.25

Quick links

Citations

2 citation in other articles

Deeply inverted electron-hole recombination in a luminescent antibody-stilbene complex.
Debler et al. (2008)
1 more

2 mentions without citation

An anti-hapten camelid antibody reveals a cryptic binding site with significant energetic contributions from a nonhypervariable loop.
Fanning et al. (2011)
1 more