Function and Biology

Crystal structure of putative TetR-family transcriptional regulator from Rhodococcus sp.

Source organism: Rhodococcus jostii RHA1
Biochemical function: DNA-binding transcription factor activity
Biological process: regulation of DNA-templated transcription
Cellular component: not assigned

Sequence families

Pfam Protein families (Pfam)
PF13977
Domain description: BetI-type transcriptional repressor, C-terminal
Occurring in:
  1. HTH tetR-type domain-containing protein
The deposited structure of PDB entry 2g3b contains 2 copies of Pfam domain PF13977 (BetI-type transcriptional repressor, C-terminal) in HTH tetR-type domain-containing protein. Showing 1 copy in chain A.

PF00440
Domain description: Bacterial regulatory proteins, tetR family
Occurring in:
  1. HTH tetR-type domain-containing protein
The deposited structure of PDB entry 2g3b contains 2 copies of Pfam domain PF00440 (Bacterial regulatory proteins, tetR family) in HTH tetR-type domain-containing protein. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001647
Domain description: DNA-binding HTH domain, TetR-type
Occurring in:
  1. HTH tetR-type domain-containing protein
IPR039538
Domain description: BetI-type transcriptional repressor, C-terminal
Occurring in:
  1. HTH tetR-type domain-containing protein
IPR036271
Domain description: Tetracyclin repressor-like, C-terminal domain superfamily
Occurring in:
  1. HTH tetR-type domain-containing protein
IPR009057
Domain description: Homedomain-like superfamily
Occurring in:
  1. HTH tetR-type domain-containing protein

Structure domain

CATH CATH domain
1.10.357.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Tetracycline Repressor; domain 2
Homology: Tetracycline Repressor, domain 2
Occurring in:
  1. HTH tetR-type domain-containing protein
The deposited structure of PDB entry 2g3b contains 2 copies of CATH domain 1.10.357.10 (Tetracycline Repressor; domain 2) in HTH tetR-type domain-containing protein. Showing 1 copy in chain A.
SCOP SCOP annotations
48499
Class: All alpha proteins
Fold: Tetracyclin repressor-like, C-terminal domain
Superfamily: Tetracyclin repressor-like, C-terminal domain
Occurring in:
  1. HTH tetR-type domain-containing protein
The deposited structure of PDB entry 2g3b contains 2 copies of SCOP domain 48499 (Tetracyclin repressor-like, C-terminal domain) in HTH tetR-type domain-containing protein. Showing 1 copy in chain A.
46764
Class: All alpha proteins
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: Homeodomain-like
Occurring in:
  1. HTH tetR-type domain-containing protein
The deposited structure of PDB entry 2g3b contains 2 copies of SCOP domain 46764 (Tetracyclin repressor-like, N-terminal domain) in HTH tetR-type domain-containing protein. Showing 1 copy in chain A.