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SOLUTION STRUCTURE OF HUMAN INSULIN-LIKE GROWTH FACTOR 1: A NUCLEAR MAGNETIC RESONANCE AND RESTRAINED MOLECULAR DYNAMICS STUDY

Source organism: Homo sapiens
Biochemical function: growth factor activity
Biological process: not assigned
Cellular component: extracellular space

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GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:

Sequence family

Pfam Protein family (Pfam)
PF00049
Domain description: Insulin/IGF/Relaxin family
Occurring in:
  1. Insulin-like growth factor 1
The deposited structure of PDB entry 2gf1 contains 1 copy of Pfam domain PF00049 (Insulin/IGF/Relaxin family) in Insulin-like growth factor 1. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR022350
Domain description: Insulin-like growth factor
Occurring in:
  1. Insulin-like growth factor 1
IPR016179
Domain description: Insulin-like
Occurring in:
  1. Insulin-like growth factor 1
IPR022341
Domain description: Insulin-like growth factor I
Occurring in:
  1. Insulin-like growth factor 1
IPR022352
Domain description: Insulin family
Occurring in:
  1. Insulin-like growth factor 1
IPR022353
Domain description: Insulin, conserved site
Occurring in:
  1. Insulin-like growth factor 1
IPR036438
Domain description: Insulin-like superfamily
Occurring in:
  1. Insulin-like growth factor 1

Structure domain

CATH CATH domain
1.10.100.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Insulin-like, subunit E
Homology: Insulin-like
Occurring in:
  1. Insulin-like growth factor 1
The deposited structure of PDB entry 2gf1 contains 1 copy of CATH domain 1.10.100.10 (Insulin-like, subunit E) in Insulin-like growth factor 1. Showing 1 copy in chain A.
SCOP SCOP annotation
56995
Class: Small proteins
Fold: Insulin-like
Superfamily: Insulin-like
Occurring in:
  1. Insulin-like growth factor 1
The deposited structure of PDB entry 2gf1 contains 1 copy of SCOP domain 56995 (Insulin-like) in Insulin-like growth factor 1. Showing 1 copy in chain A.

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