› 2gfh

X-ray diffraction
1.9Å resolution

Crystal structure of a n-acetylneuraminic acid phosphatase (nanp) from mus musculus at 1.90 A resolution

Released:
DOI: 10.2210/pdb2gfh/pdb
Model geometry
Fit model/data
PDB entry 2gfh coloured by chain, front view.
PDB entry 2gfh coloured by chain, side view.
PDB entry 2gfh coloured by chain, top view.
Source organism: Mus musculus
Entry author: Joint Center for Structural Genomics (JCSG)

Function and Biology Details

Reaction catalysed: 
N-acylneuraminate 9-phosphate + H(2)O = N-acylneuraminate + phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-189991 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
N-acylneuraminate-9-phosphatase Chain: A
Molecule details ›
Chain: A
Length: 260 amino acids
Theoretical weight: 29.3 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9CPT3 (Residues: 1-248; Coverage: 100%)
Gene names: Hdhd4, Nanp
Sequence domains: haloacid dehalogenase-like hydrolase
Structure domains:

Ligands and Environments

4 bound ligands:
Ligand NA 1 x NA
Ligand CL 1 x CL
Ligand PO4 1 x PO4
Ligand EDO 1 x EDO
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: ALS BEAMLINE 5.0.3
Spacegroup: P6122
Unit cell:
a: 71.259Å b: 71.259Å c: 195.632Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.21 0.208 0.259
Expression system: Escherichia coli

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