Function and Biology

Xray Structure of Gag278

Source organism: Human immunodeficiency virus 1
Biochemical function: structural molecule activity
Biological process: viral process
Cellular component: not assigned

GO terms

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF00607
Domain description: gag protein p24 N-terminal domain
Occurring in:
  1. Retroviral nucleocapsid Gag protein p24 C-terminal domain-containing protein
The deposited structure of PDB entry 2gol contains 2 copies of Pfam domain PF00607 (gag protein p24 N-terminal domain) in Retroviral nucleocapsid Gag protein p24 C-terminal domain-containing protein. Showing 1 copy in chain B.

PF00540
Domain description: gag gene protein p17 (matrix protein)
Occurring in:
  1. Immunodeficiency lentiviral matrix N-terminal domain-containing protein
The deposited structure of PDB entry 2gol contains 1 copy of Pfam domain PF00540 (gag gene protein p17 (matrix protein)) in Immunodeficiency lentiviral matrix N-terminal domain-containing protein. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR000071
Domain description: Immunodeficiency lentiviral matrix, N-terminal
Occurring in:
  1. Immunodeficiency lentiviral matrix N-terminal domain-containing protein
IPR000721
Domain description: Retroviral nucleocapsid Gag protein p24, N-terminal
Occurring in:
  1. Retroviral nucleocapsid Gag protein p24 C-terminal domain-containing protein
IPR008919
Domain description: Retrovirus capsid, N-terminal
Occurring in:
  1. Retroviral nucleocapsid Gag protein p24 C-terminal domain-containing protein
IPR012344
Domain description: Matrix protein, lentiviral and alpha-retroviral, N-terminal
Occurring in:
  1. Immunodeficiency lentiviral matrix N-terminal domain-containing protein
IPR010999
Domain description: Retroviral matrix protein
Occurring in:
  1. Immunodeficiency lentiviral matrix N-terminal domain-containing protein

Structure domains

CATH CATH domains
1.10.375.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Human Immunodeficiency Virus Type 1 Capsid Protein
Homology: Human Immunodeficiency Virus Type 1 Capsid Protein
Occurring in:
  1. Retroviral nucleocapsid Gag protein p24 C-terminal domain-containing protein
The deposited structure of PDB entry 2gol contains 2 copies of CATH domain 1.10.375.10 (Human Immunodeficiency Virus Type 1 Capsid Protein) in Retroviral nucleocapsid Gag protein p24 C-terminal domain-containing protein. Showing 1 copy in chain B.
1.10.150.90
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: DNA polymerase; domain 1
Homology: Immunodeficiency lentiviruses, gag gene matrix protein p17
Occurring in:
  1. Immunodeficiency lentiviral matrix N-terminal domain-containing protein
The deposited structure of PDB entry 2gol contains 1 copy of CATH domain 1.10.150.90 (DNA polymerase; domain 1) in Immunodeficiency lentiviral matrix N-terminal domain-containing protein. Showing 1 copy in chain A.
SCOP SCOP annotations
47944
Class: All alpha proteins
Fold: Retrovirus capsid protein, N-terminal core domain
Superfamily: Retrovirus capsid protein, N-terminal core domain
Occurring in:
  1. Retroviral nucleocapsid Gag protein p24 C-terminal domain-containing protein
The deposited structure of PDB entry 2gol contains 2 copies of SCOP domain 47944 (Retrovirus capsid protein, N-terminal core domain) in Retroviral nucleocapsid Gag protein p24 C-terminal domain-containing protein. Showing 1 copy in chain B.
47837
Class: All alpha proteins
Fold: Retroviral matrix proteins
Superfamily: Retroviral matrix proteins
Occurring in:
  1. Immunodeficiency lentiviral matrix N-terminal domain-containing protein
The deposited structure of PDB entry 2gol contains 1 copy of SCOP domain 47837 (Immunodeficiency virus matrix proteins) in Immunodeficiency lentiviral matrix N-terminal domain-containing protein. Showing 1 copy in chain A.